Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.75 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | DRD1 | P21728 | 1/20 | 0.75 |
| ▸ | DRD5 | P21918 | 1/20 | 0.75 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727789 | 0.97 | CHRM2 (0.73) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9727985 | 0.93 | CHRM2 (0.65) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL10517009 | 0.93 | CHRM2 (0.66) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9728115 | 0.89 | CHRM2 (0.64) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9674192 | 0.89 | CHRM2 (0.60) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9728271 | 0.89 | CHRM2 (0.78) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9676282 | 0.88 | CHRM2 (0.60) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL8880640 | 0.88 | CHRM2 (0.77) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL10969022 | 0.88 | LMNA (0.81) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL10709094 | 0.88 | LMNA (0.81) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312895-A2 | Condensed diazepinones, process for their preparation and medicament containing them | Dr. Karl Thomae GmbH (DE) | 1989-04-26 | — | — | EP | claimed |
| JP-1230580-A | — | — | None | — | — | JP | disclosed |
| US-5175158-A | CONDENSED DIAZEPINONES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | DR. KARL THOMAE, GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| JP-H01230580-A | CONDENSED DIAZEPINONE, ITS PREPARATION AND PHARMACEUTIC CONTAINING THAT COMPOUND | DR KARL THOMAE GMBH | 1989-09-14 | — | — | JP | disclosed |
| EP-0312895-A2 | Condensed diazepinones, process for their preparation and medicament containing them | Dr. Karl Thomae GmbH (DE) | 1989-04-26 | — | — | EP | disclosed |