Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520440 | 0.77 | HTT (0.47) | MAPTALDH1A1NPC1HSD17B10GFER | |
| SCHEMBL10519173 | 0.76 | ALDH1A1 (0.41) | MAPTALDH1A1NPC1HSD17B10GFER | |
| SCHEMBL10518279 | 0.75 | EHMT2 (0.44) | MAPTALDH1A1NPC1HSD17B10GFER | |
| SCHEMBL18724191 | 0.75 | MAPT (0.53) | MAPTALDH1A1NPC1HSD17B10GFER | |
| SCHEMBL10520814 | 0.74 | MAPT (0.64) | MAPTALDH1A1NPC1HSD17B10GFER | |
| SCHEMBL1665356 | 0.73 | ALDH1A1 (0.48) | MAPTALDH1A1NPC1HSD17B10GFER | |
| SCHEMBL16003687 | 0.73 | ALDH1A1 (0.58) | MAPTALDH1A1NPC1HSD17B10GFER | |
| SCHEMBL13825294 | 0.72 | LTA4H (0.67) | MAPTALDH1A1NPC1CYP3A4LTA4H | |
| SCHEMBL10519613 | 0.70 | ALDH1A1 (0.59) | MAPTALDH1A1NPC1HSD17B10GFER | |
| SCHEMBL27589585 | 0.70 | ALDH1A1 (0.61) | MAPTALDH1A1NPC1HSD17B10GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |