Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18293426 | 0.84 | ALDH1A1 (0.42) | KCNH2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL26804195 | 0.84 | NOS3 (0.47) | KCNH2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL26647445 | 0.80 | MAPT (0.50) | KCNH2ALDH1A1KMT2APOLBPKM | |
| SCHEMBL913896 | 0.79 | MAP4K4 (0.43) | KCNH2KDM4E | |
| SCHEMBL18293428 | 0.78 | PIK3C3 (0.40) | KCNH2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11642192 | 0.77 | ALDH1A1 (0.61) | KCNH2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL2252618 | 0.72 | KDM4E (0.58) | KCNH2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3064504 | 0.72 | PIK3C3 (0.42) | KCNH2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL914479 | 0.71 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL3709323 | 0.70 | ALDH1A1 (0.68) | ALDH1A1POLBPKMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308917-A2 | Imidazopyridine compound, a process for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |