Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TYMS | P04818 | 3/20 | 0.47 |
| ▸ | DHFR | P00374 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516611 | 0.91 | MAPT (0.53) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10516456 | 0.91 | ALDH1A1 (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10516058 | 0.90 | ALDH1A1 (0.51) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10519474 | 0.88 | DHFR (0.52) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10521296 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10516552 | 0.87 | ALDH1A1 (0.46) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10522322 | 0.85 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10521999 | 0.81 | ALDH1A1 (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10517551 | 0.78 | MAPT (0.62) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10517534 | 0.78 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797146-A | INSECTICIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| EP-0226885-A1 | Pyrimidylmercapto-acylanilides | BAYER AG (DE) | 1987-07-01 | — | — | EP | disclosed |