Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 2/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 3/20 | 0.32 |
| ▸ | LIG1 | P18858 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879638 | 0.79 | GSK3B (0.34) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL9669214 | 0.67 | GSK3B (0.37) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL5575063 | 0.67 | NR1H2 (0.36) | LMNASMN1; SMN2MAPK1TTRLRRK2 | |
| Phthalimide SCHEMBL4318901 | 0.66 | GSK3B (0.71) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL15488735 | 0.65 | GSK3B (0.79) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL11492689 | 0.64 | GSK3B (0.68) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL7297919 | 0.63 | GSK3B (0.75) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL1132405 | 0.63 | GSK3B (0.75) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL28353587 | 0.63 | GSK3B (0.65) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalic Acid SCHEMBL28249734 | 0.63 | GSK3B (0.65) | GSK3BCASP3CASP7CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309422-A2 | New amidino tricycle derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |