Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517673 | 0.79 | GSK3B (0.38) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL29036210 | 0.69 | PTGS2 (0.55) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL9669214 | 0.63 | GSK3B (0.37) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL3351153 | 0.62 | KDM4E (0.49) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL4318901 | 0.62 | GSK3B (0.71) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL15488735 | 0.62 | GSK3B (0.79) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL2319609 | 0.62 | GSK3B (0.52) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL27564000 | 0.62 | GSK3B (0.52) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL5306954 | 0.61 | GSK3B (0.62) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL11492689 | 0.61 | GSK3B (0.68) | GSK3BCASP3CASP2CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |