Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.54 |
| ▸ | KLK1 | P06870 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308535 | 0.81 | CES2 (0.58) | CES2CES1F2PLGPLAU | |
| SCHEMBL30161362 | 0.77 | CES2 (0.87) | CES2CES1MEN1KMT2AMAPT | |
| SCHEMBL30500514 | 0.77 | CES2 (0.54) | CES2CES1F2PLGPLAU | |
| SCHEMBL124894 | 0.77 | MEN1 (0.75) | CES2CES1MEN1KMT2AMAPT | |
| SCHEMBL15478714 | 0.77 | PLAU (0.61) | CES2CES1F2PLGPLAU | |
| SCHEMBL29834246 | 0.77 | MEN1 (0.75) | CES2CES1MEN1KMT2AMAPT | |
| SCHEMBL4088285 | 0.77 | CES2 (0.54) | CES2CES1F2PLGPLAU | |
| Beta-Naphtoic Acid SCHEMBL9008562 | 0.77 | CES2 (0.65) | CES2CES1MEN1KMT2AMAPT | |
| SCHEMBL14876982 | 0.77 | CES2 (0.87) | CES2CES1MEN1KMT2AMAPT | |
| SCHEMBL2837486 | 0.77 | CES2 (0.65) | CES2CES1F2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323864-A2 | Lipophilic oxadiazoles | MERCK SHARP & DOHME LTD. (GB) | 1989-07-12 | — | — | EP | disclosed |