SCHEMBL4088285

SCHEMBL4088285

C=C(c1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 1/20 0.50
EGFR P00533 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
PKM P14618 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
JAK1 P23458 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
F2 P00734 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30500514 1.00 CES2 (0.54) CES2CES1MEN1KMT2AMAPT
SCHEMBL22288260 0.86 CES2 (0.52) CES2CES1MEN1KMT2AMAPT
Anthracene SCHEMBL27473759 0.86 MEN1 (0.50) CES2CES1MEN1KMT2AMAPT
Naphthalene SCHEMBL27921575 0.86 MEN1 (0.54) CES2CES1MEN1KMT2AMAPT
SCHEMBL3163567 0.84 NPC1 (0.53) CES2CES1MEN1KMT2AMAPT
SCHEMBL7763051 0.83 CYP2A6 (0.50) CES2CES1MEN1KMT2AMAPT
SCHEMBL8242356 0.82 CES2 (0.58) CES2CES1MEN1KMT2AMAPT
SCHEMBL894135 0.81 MEN1 (0.65) CES2CES1MEN1KMT2AMAPT
SCHEMBL3172743 0.80 NPC1 (0.56) CES2CES1MEN1KMT2AMAPT
SCHEMBL814654 0.79 MEN1 (0.52) CES2CES1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4734824-A MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-29 US claimed
CN-113773227-B Method for preparing epsilon-, zeta-, eta-cyano carboxylic acid from carbon dioxide 常州大学 2023-07-25 CN disclosed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
CN-113773227-A Method for preparing epsilon-, zeta-, eta-cyano carboxylic acid from carbon dioxide 常州大学 2021-12-10 CN disclosed
CN-112608222-A Method for preparing aldehyde ketone compound by olefin oxidation 三峡大学 2021-04-06 CN disclosed
CN-111517902-A Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2020-08-11 CN disclosed
WO-2020155595-A1 AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR 清华大学 2020-08-06 WO disclosed
CN-100512582-C Light emitting system, light emitting method and chemical substance for light emission HITACHI CHEMICAL CO LTD (JP) 2009-07-08 CN disclosed
US-20090163743-A1 LUMINESCENCE SYSTEM, METHOD OF LUMINESCENCE, AND CHEMICAL SUBSTANCE FOR LUMINESCENCE HOSHI YOUSUKE 2009-06-25 US disclosed
US-20070138945-A1 Luminescence system, method of luminescence, and chemical substance for luminescence HITACHI CHIEMICAL CO., LTD., (JP) 2007-06-21 US disclosed
CN-1898995-A Light emitting system, light emitting method and chemical substance for light emission HITACHI CHEMICAL CO LTD (JP) 2007-01-17 CN disclosed
US-4994539-A Ethylene-unsaturated aromatic copolymer NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-19 US disclosed
EP-0180771-B1 METHOD FOR IMPROVING IMPULSE BREAKDOWN STRENGTH OF ELECTRICALLY INSULATING MATERIALS Nippon Petrochemicals Co., Ltd. (JP) 1989-08-02 EP disclosed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed
US-4734824-A MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-29 US disclosed
EP-0154993-B1 ELECTRICAL INSULATING OIL AND ELECTRICAL APPLIANCES IMPREGNATED WITH THE SAME NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-09 EP disclosed
US-4621302-A MONO-OR DIOLEFIN HAVING THREE CONDENSED OR NON-CONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-11-04 US disclosed
EP-0180771-A1 Method for improving impulse breakdown strength of electrically insulating materials Nippon Petrochemicals Co., Ltd. (JP) 1986-05-14 EP disclosed
EP-0154993-A1 Electrical insulating oil and electrical appliances impregnated with the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070138945-A1 Luminescence system, method of luminescence, and chemical substance for luminescence GLO1, TYR, GUSB CES2 9/4885CES1 674/4885MEN1 2406/4885
US-20090163743-A1 LUMINESCENCE SYSTEM, METHOD OF LUMINESCENCE, AND CHEMICAL SUBSTANCE FOR LUMINESCENCE GLO1, TYR, GUSB CES2 9/4885CES1 674/4885MEN1 2406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.