Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483573 | 0.88 | MEN1 (0.40) | MAPTCYP1A2MEN1KMT2AIDO1 | |
| SCHEMBL10516167 | 0.83 | PARP1 (0.37) | MAPTCYP1A2TSHRCASP1MEN1 | |
| SCHEMBL10516856 | 0.82 | CSNK1G1 (0.41) | MAPTCASP1DRD4LMNAHSD17B10 | |
| SCHEMBL10515295 | 0.80 | PARP1 (0.39) | MAPTCYP1A2TSHRCASP1MEN1 | |
| SCHEMBL10515664 | 0.79 | POLB (0.38) | CYP1A2CYP2C9TSHRCYP2C19CASP1 | |
| SCHEMBL10514837 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2A | |
| SCHEMBL10517669 | 0.78 | DAO (0.38) | MAPTMEN1KMT2ADRD4LMNA | |
| SCHEMBL10514845 | 0.76 | CHRM2 (0.40) | MAPTCASP1CHRM2CHRM4CYP3A4 | |
| SCHEMBL10515428 | 0.76 | ALDH1A1 (0.39) | HRH3MAPTMEN1KMT2AIDO1 | |
| SCHEMBL10516012 | 0.76 | POLB (0.37) | CYP1A2CYP2C9TSHRCYP2C19CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326526-A1 | Aminoketones of substituted dibenzo- and pyridobenzo-azepinones and pharmaceutical compositions | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-08-02 | — | — | EP | disclosed |