Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516012 | 0.93 | POLB (0.37) | POLBMEN1KMT2APBRM1TNKS2 | |
| SCHEMBL10516167 | 0.89 | PARP1 (0.37) | MEN1KMT2ATNKS2KDM4EGLA | |
| SCHEMBL10514837 | 0.88 | ALDH1A1 (0.38) | MEN1KMT2APBRM1TNKS2ALDH1A1 | |
| SCHEMBL10483573 | 0.88 | MEN1 (0.40) | MEN1KMT2AKDM4EGLAALDH1A1 | |
| SCHEMBL10515379 | 0.87 | DRD2 (0.35) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10517669 | 0.86 | DAO (0.38) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10515295 | 0.84 | PARP1 (0.39) | MEN1KMT2ATNKS2KDM4EGLA | |
| SCHEMBL10516856 | 0.84 | CSNK1G1 (0.41) | KDM4EGLAALDH1A1HPGDCASP1 | |
| SCHEMBL10517260 | 0.83 | SMARCA2 (0.37) | MEN1KMT2APBRM1TNKS2ALDH1A1 | |
| SCHEMBL10518481 | 0.79 | HRH4 (0.40) | POLBMEN1KMT2ACASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326526-A1 | Aminoketones of substituted dibenzo- and pyridobenzo-azepinones and pharmaceutical compositions | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-08-02 | — | — | EP | disclosed |