Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 5/20 | 0.35 |
| ▸ | PTPRG | P23470 | 5/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26765459 | 0.74 | KMT2A (0.51) | KMT2A | |
| Hydrochloric Acid SCHEMBL9334343 | 0.73 | KMT2A (0.50) | KMT2A | |
| SCHEMBL6550959 | 0.73 | KMT2A (0.67) | KMT2APTPRCPTPRGMAPTIDO1 | |
| SCHEMBL4634541 | 0.69 | KMT2A (0.36) | KMT2AMAPTHSD17B10 | |
| SCHEMBL17629372 | 0.69 | MAPT (0.33) | KMT2AMAPT | |
| SCHEMBL8794570 | 0.67 | PTPRC (0.56) | KMT2APTPRCPTPRGMAPT | |
| SCHEMBL9534144 | 0.67 | LCK (0.33) | KMT2A | |
| SCHEMBL3671086 | 0.66 | KMT2A (0.33) | KMT2AMAPTHSD17B10 | |
| SCHEMBL9351950 | 0.66 | GSK3B (0.41) | KMT2AMAPT | |
| SCHEMBL10587921 | 0.66 | KMT2A (0.37) | KMT2APTPRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318682-A2 | Tricyclic thiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-06-07 | — | — | EP | disclosed |