Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609300 | 0.86 | RAB9A (0.37) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL3807655 | 0.84 | MEN1 (0.34) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4607918 | 0.82 | KDM4E (0.36) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL27617435 | 0.81 | ESR1 (0.41) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL3671086 | 0.77 | KMT2A (0.33) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL9351950 | 0.77 | GSK3B (0.41) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL10587921 | 0.77 | KMT2A (0.37) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL9416574 | 0.76 | HDAC3 (0.39) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4636562 | 0.75 | MAPT (0.40) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL10369277 | 0.75 | KDM4E (0.33) | KMT2AMEN1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |