Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635290 | 0.90 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL29376920 | 0.90 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL11235716 | 0.88 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL10618700 | 0.84 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL7517643 | 0.84 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL30540821 | 0.84 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL19971590 | 0.84 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL15999499 | 0.82 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL13368169 | 0.82 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 | |
| SCHEMBL1345017 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19CLEC4MGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184384-B1 | SUBSTITUTED DIHYDROQUINOLONE CARBOXYLIC ACIDS, ANTI-BACTERIAL COMPOSITIONS CONTAINING THEM | PFIZER INC. (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4623650-A | BACTERICIDES | PFIZER INC. (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0184384-A1 | Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them | PFIZER INC. (US) | 1986-06-11 | — | — | EP | disclosed |