Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540821 | 1.00 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL9635290 | 0.91 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL29376920 | 0.91 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL30540807 | 0.88 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL28408020 | 0.88 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL11235716 | 0.86 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL28405596 | 0.86 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19CLEC4MMAPT | |
| SCHEMBL30540819 | 0.86 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19CLEC4MMAPT | |
| SCHEMBL1345017 | 0.85 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL10519082 | 0.84 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158862-A2 | STIMULATOR OF INTERFERON GENES (STING) MODULATORS, AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| CN-111170941-A | Preparation method of 1-cyclopropyl-6, 7-difluoro-8-methoxy fluoroquinolone-3-carboxylic ester | 江西农业大学 | 2020-05-19 | — | — | CN | disclosed |
| US-10654869-B2 | Bacterial topoisomerase I inhibitors with antibacterial activity | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2020-05-19 | — | — | US | disclosed |
| US-10654869-B2 | Bacterial topoisomerase I inhibitors with antibacterial activity | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190194224-A1 | BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2019-06-27 | — | — | US | disclosed |
| US-20190194224-A1 | BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2019-06-27 | — | — | US | disclosed |
| US-10266550-B2 | Bacterial topoisomerase I inhibitors with antibacterial activity | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2019-04-23 | — | — | US | disclosed |
| US-10266550-B2 | Bacterial topoisomerase I inhibitors with antibacterial activity | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2019-04-23 | — | — | US | disclosed |
| US-20180079757-A1 | BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2018-03-22 | — | — | US | disclosed |
| US-20180079757-A1 | BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079757-A1 | BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY | TOP1, TOP2A, TOP2B | CYP1A2 1365/4885CYP3A4 1902/4885CYP2C19 955/4885 |
| US-10654869-B2 | Bacterial topoisomerase I inhibitors with antibacterial activity | TOP1, TOP2A, TOP2B | CYP1A2 1365/4885CYP3A4 1902/4885CYP2C19 955/4885 |
| US-10266550-B2 | Bacterial topoisomerase I inhibitors with antibacterial activity | TOP1, TOP2A, TOP2B | CYP1A2 1365/4885CYP3A4 1902/4885CYP2C19 955/4885 |
| US-20190194224-A1 | BACTERIAL TOPOISOMERASE I INHIBITORS WITH ANTIBACTERIAL ACTIVITY | TOP1, TOP2A, TOP2B | CYP1A2 1537/4885CYP3A4 2075/4885CYP2C19 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.