SCHEMBL1051965

SCHEMBL1051965

C[n+]1cccc2ccccc21.[C-]#N

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 11/20 0.48
BCHE P06276 8/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29752612 0.93 ACHE (0.53) ACHEBCHE
SCHEMBL307903 0.93 ACHE (0.53) ACHEBCHE
Iodide SCHEMBL28357633 0.91 ACHE (0.52) ACHEBCHE
Hydrochloric Acid SCHEMBL2031419 0.91 ACHE (0.52) ACHEBCHE
Hydrochloric Acid SCHEMBL30383932 0.91 ACHE (0.52) ACHEBCHE
Iodide SCHEMBL29462685 0.91 ACHE (0.55) ACHEBCHE
Bromide SCHEMBL7776277 0.91 ACHE (0.52) ACHEBCHE
Bromide SCHEMBL5611688 0.91 ACHE (0.52) ACHEBCHE
Iodide SCHEMBL29462677 0.91 ACHE (0.52) ACHEBCHE
Hydrochloric Acid SCHEMBL27855884 0.91 ACHE (0.52) ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382425-B2 Aza-benzazolium containing cyanine dyes Life Technologies Corporation (US) 2016-07-05 US disclosed
US-20150031579-A1 Aza-Benzazolium Containing Cyanine Dyes MOLECULAR PROBES, INC. 2015-01-29 US disclosed
US-8883415-B2 Aza-benzazolium containing cyanine dyes Life Technologies Corporation (US) 2014-11-11 US disclosed
US-20130178395-A1 Aza-Benzazolium Containing Cyanine Dyes Life Technologies Corporation (US) 2013-07-11 US disclosed
US-20120295817-A1 Aza-benzazolium Containing Cyanine Dyes Life Technologies Corporation (US) 2012-11-22 US disclosed
US-8252530-B2 Aza-benzazolium containing cyanine dyes Life Technologies Corporation (US) 2012-08-28 US disclosed
US-20110217696-A1 AZA-BENZAZOLIUM CONTAINING CYANINE DYES Life Technologies Corporation (US) 2011-09-08 US disclosed
US-7871773-B2 nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected Life Technologies Corporation (US) 2011-01-18 US disclosed
US-20080044811-A1 nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected INVITROGEN CORPORATION (US) 2008-02-21 US disclosed
US-7226740-B2 nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected INVITROGEN CORPORATION (US) 2007-06-05 US disclosed
US-20040137475-A1 nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected Life Technologies Corporation 2004-07-15 US disclosed
US-6664047-B1 Assymetrical; substituted by a cationic side chain; exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or with polypeptides MOLECULAR PROBES, INC. 2003-12-16 US disclosed
US-5656449-A STAINING NUCLEIC ACIDS MOLECULAR PROBES, INC. (US) 1997-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040137475-A1 nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected POLL, IK, ADAR ACHE 3907/4885BCHE 3001/4885
US-20110217696-A1 AZA-BENZAZOLIUM CONTAINING CYANINE DYES AZI2, BRDT, DNMT1 ACHE 1507/4885BCHE 1661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.