Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337641 | 0.80 | KDM1A (0.47) | KDM1ASYKMAPTALDH1A1KDM4E | |
| SCHEMBL26074092 | 0.80 | APP (0.49) | KDM1ADHODHSYKTP53ALDH1A1 | |
| SCHEMBL12151481 | 0.73 | APP (0.46) | SYKMAPTSMN1; SMN2APP | |
| SCHEMBL10517623 | 0.73 | PDGFRB (0.51) | KDM1ASYKMAPTALDH1A1KDM4E | |
| SCHEMBL26075314 | 0.71 | APP (0.43) | KDM1ADHODHMEN1KMT2AAPP | |
| SCHEMBL2539892 | 0.70 | KDM4E (0.58) | KDM1ADHODHALDH1A1KDM4ELMNA | |
| SCHEMBL26075893 | 0.69 | ESR1 (0.37) | KDM1ASYKAPP | |
| SCHEMBL13568539 | 0.69 | CYP3A4 (0.53) | KDM1ADHODHSYKTP53MAPT | |
| SCHEMBL10118808 | 0.68 | ESR1 (0.51) | DHODHTP53MAPTALDH1A1KDM4E | |
| SCHEMBL14188099 | 0.68 | ALDH1A1 (0.52) | TP53MAPTALDH1A1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339518-A2 | Quinoline compounds and their use | BASF Aktiengesellschaft (DE) | 1989-11-02 | — | — | EP | disclosed |