Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 7/20 | 0.47 |
| ▸ | APP | P05067 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517623 | 0.86 | PDGFRB (0.51) | KDM1ASYKAPPALDH1A1MAPT | |
| SCHEMBL10519151 | 0.82 | KDM1A (0.41) | KDM1ASYKAPPCYP3A4ALDH1A1 | |
| SCHEMBL26074092 | 0.81 | APP (0.49) | KDM1ASYKAPPCYP3A4ALDH1A1 | |
| SCHEMBL12151481 | 0.80 | APP (0.46) | SYKAPPMAPTSMN1; SMN2 | |
| SCHEMBL10519962 | 0.80 | KDM1A (0.50) | KDM1ASYKAPPCYP3A4ALDH1A1 | |
| Dimethylamine SCHEMBL10337642 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10682375 | 0.74 | MAPK14 (0.53) | KDM1AAPPALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26075314 | 0.72 | APP (0.43) | KDM1AAPPMEN1KMT2A | |
| SCHEMBL10518948 | 0.72 | PDGFRB (0.46) | KDM1ASYKCYP3A4ALDH1A1MAPT | |
| SCHEMBL8618775 | 0.71 | MAPT (0.54) | SYKAPPALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011571-A | — | — | None | — | — | JP | disclosed |
| JP-H0211571-A | QUINOLINE COMPOUND AND ITS USE | BASF AG | 1990-01-16 | — | — | JP | disclosed |
| EP-0339518-A2 | Quinoline compounds and their use | BASF Aktiengesellschaft (DE) | 1989-11-02 | — | — | EP | disclosed |