Sulforaphane

Sulforaphane

SCHEMBL105202

C[S+]([O-])CCCCN=C=S

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 4/20 0.50
TRPA1 O75762 8/20 0.47
MIF P14174 5/20 0.45
KEAP1 Q14145 2/20 0.44
NFE2L2 Q16236 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
BACH1 O14867 1/20 0.44
MAFK O60675 1/20 0.44
EGFR P00533 1/20 0.44
PTGS2 P35354 1/20 0.44
GSK3B P49841 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulforaphane SCHEMBL17629812 1.00 NAAA (0.50) NAAATRPA1MIFKEAP1NFE2L2
Sulforaphane SCHEMBL105203 1.00 NAAA (0.50) NAAATRPA1MIFKEAP1NFE2L2
Sulforaphane SCHEMBL20855320 1.00 NAAA (0.50) NAAATRPA1MIFKEAP1NFE2L2
L-Sulforaphane SCHEMBL29370377 1.00 NAAA (0.50) NAAATRPA1MIFKEAP1NFE2L2
Sulforaphane SCHEMBL15822685 1.00 NAAA (0.50) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL25332541 0.98 NAAA (0.54) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL1607124 0.98 NAAA (0.54) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL14933784 0.98 NAAA (0.54) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL2485837 0.98 NAAA (0.54) NAAATRPA1MIFKEAP1NFE2L2
SCHEMBL106183 0.98 NAAA (0.54) NAAATRPA1MIFKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10401 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746880-A2 METHODS OF TREATING DILATED CARDIOMYOPATHY Regencor, Inc. (US) 2026-05-27 EP claimed
CN-122075798-A Three-dimensional porous bioactive scaffold, vascularized bone organ and preparation method and application thereof 2026-05-26 CN claimed
US-12635720-B2 Prepared foods having high efficacy omega-6/omega-3 balanced polyunsaturated fatty acids OMEGA FOODS LLC (US) 2026-05-26 US claimed
CN-122074540-A Rosemary serving as preservative and extraction process thereof 2026-05-26 CN claimed
US-20260139320-A1 StarTrace: A Multiplex Drug Testing Platform for Personalized Medicine UNIV OF SOUTH CAROLINA (US) 2026-05-21 US claimed
CN-122031543-A A medicinal and edible composition for preventing and improving pulmonary nodule and pulmonary fibrosis, and its preparation method and application 南京中医药大学 2026-05-15 CN claimed
CN-122038303-A Induction system for improving reprogramming efficiency of somatic cells and reprogramming method 广州医科大学附属第五医院(广州再生医学与健康广东省实验室附属医院) 2026-05-15 CN claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
US-12622857-B2 Skin lightening composition Bella Aurora Labs, S.A. (ES) 2026-05-12 US claimed
US-20260124284-A1 COMPOSITIONS COMPRISING SULFORAPHANE OR A SULFORAPHANE PRECURSOR AND A MILK THISTLE EXTRACT OR POWDER NUTRAMAX LAB INC (US) 2026-05-07 US claimed
WO-2002002190-A2 PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES BY GLUTATHIONE AND PHASE II DETOXIFICATION ENZYMES JOHNS HOPKINS SCHOOL OF MEDICINE (US) 2002-01-10 WO claimed
WO-2001045661-A2 COSMETIC AND/OR PHARMACEUTICAL PREPARATIONS COGNIS FRANCE, S.A. (FR) 2001-06-28 WO claimed
EP-1100517-A1 NUTRIENT AND THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF CANCER Kosbab, John V. (US) 2001-05-23 EP claimed
WO-2000045829-A1 BRASSICA EXTRACTS OR SULFORAPHANE IN COMBINATION WITH RESVERATROL AS ANTITUMOR AGENTS WASSEN INTERNATIONAL LIMITED (GB) 2000-08-10 WO claimed
US-RE36784-E Chemoprotective isothiocyanates THE JOHNS HOPKINS UNIVERSITY (US) 2000-07-18 US claimed
WO-2000007607-A1 NUTRIENT AND THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF CANCER KOSBAB, JOHN, V. (US) 2000-02-17 WO claimed
US-5686108-A Brassica vegetable supplement and process for manufacture AMWAY CORPORATION (US) 1997-11-11 US claimed
US-5411986-A Chemoprotective isothiocyanates THE JOHNS HOPKINS UNIVERSITY (US) 1995-05-02 US claimed
WO-1994019948-A9 CHEMOPROTECTIVE ISOTHIOCYANATES 1994-11-10 WO claimed
WO-1994019948-A1 CHEMOPROTECTIVE ISOTHIOCYANATES CHO CHEON GYU (US) 1994-09-15 WO claimed