SCHEMBL105204

SCHEMBL105204

COc1[c]cc(OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA12 O43570 2/20 0.48
CA14 Q9ULX7 2/20 0.48
ACHE P22303 1/20 0.40
TDP1 Q9NUW8 3/20 0.39
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
RECQL P46063 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27488332 0.98 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL28053489 0.98 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL27274696 0.95 CA1 (0.43) CA1CA2CA7CA9CA12
SCHEMBL27493759 0.91 CA1 (0.40) CA1CA2CA7CA9CA12
Magnesium Chloride Anhydrous SCHEMBL28224231 0.91 CA1 (0.40) CA1CA2CA7CA9CA12
SCHEMBL29242304 0.88 CA1 (0.37) CA1CA2CA7CA9CA12
SCHEMBL4820299 0.82 ESR2 (0.48) CA1CA2CA7CA9CA12
SCHEMBL8047364 0.82 ALDH1A3 (0.39) CA1CA2CA7CA9CA12
SCHEMBL2454340 0.81 NQO1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL1069758 0.81 MAPT (0.37) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5084 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114369011-B New green method for preparing 2-diaryl methyl substituted-1-naphthol compound 湖南理工学院 2024-07-09 CN claimed
US-20240182471-A1 METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2024-06-06 US claimed
US-20240174603-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME RAPPTA THERAPEUTICS OY (FI) 2024-05-30 US claimed
EP-3253737-B3 AUTOTAXIN INHIBITORY COMPOUNDS CANCER RESEARCH TECH LTD (GB) 2024-05-29 EP claimed
CN-117983302-A Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
CN-117623838-A Chiral sulfoxide ester compound and preparation method thereof 贵州大学 2024-03-01 CN claimed
CN-117624092-A Method for preparing N-diaryl methyl substituted-2-amino furan compound 湖南理工学院 2024-03-01 CN claimed
US-11912704-B2 Methods and compositions for substituted arylcycloheptane analogs UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2024-02-27 US claimed
CN-115925527-B Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2024-02-09 CN claimed
CN-117534632-A Dibenzophenoselenazine compound and preparation method and application thereof 中山大学 2024-02-09 CN claimed
EP-0034443-A2 Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1981-08-26 EP claimed
US-4255181-A Use of substituted-3-phenacylidenephthalides as corn plant growth regulants MONSANTO COMPANY (US) 1981-03-10 US claimed
US-4239764-A FOR SLOWING HEART RATE BOEHRINGER INGELHEIM GMBH (DE) 1980-12-16 US claimed
EP-0013172-A2 Electrophotographic elements Ricoh Company, Ltd (JP) 1980-07-09 EP claimed
EP-0012611-A2 Electrophotographic element Ricoh Company, Ltd (JP) 1980-06-25 EP claimed
US-4185989-A MIXTURE OF HERBICIDE APPLY TO RICE PLANTS MONSANTO COMPANY (US) 1980-01-29 US claimed
US-4182622-A REDUCE HERBICIDAL INJURY TO RICE PLANTS MONSANTO COMPANY (US) 1980-01-08 US claimed
US-4118561-A ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY AMERICAN HOME PRODUCTS CORPORATION (US) 1978-10-03 US claimed
US-4108880-A ULTRAVIOLET ABSORBERS JOHNSON & JOHNSON (US) 1978-08-22 US claimed
US-3981716-A CORN, WEEDS STAUFFER CHEMICAL COMPANY (US) 1976-09-21 US claimed