Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064959 | 0.86 | MAPT (0.40) | MAPTKDM4EDRD1POLBMEN1 | |
| SCHEMBL900696 | 0.85 | DRD1 (0.38) | MAPTKDM4EDRD1POLBMEN1 | |
| SCHEMBL8047364 | 0.82 | ALDH1A3 (0.39) | POLBKMT2AALDH1A1LMNACA12 | |
| SCHEMBL105204 | 0.81 | CA1 (0.48) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28053489 | 0.79 | CA1 (0.46) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27488332 | 0.79 | CA1 (0.46) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1064079 | 0.77 | GPR3 (0.34) | MAPTDRD1MEN1KMT2AALDH1A1 | |
| SCHEMBL27274696 | 0.77 | CA1 (0.43) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1067320 | 0.75 | DRD1 (0.37) | MAPTKDM4EDRD1POLBMEN1 | |
| SCHEMBL160011 | 0.74 | GPR3 (0.35) | MAPTALDH1A1CCR6CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006886-A2 | AZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT XIV | BASF SE (DE) | 2011-01-20 | — | — | WO | disclosed |
| WO-2010149758-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2010-12-29 | — | — | WO | disclosed |