Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL10517322 | 0.92 | ELOVL1 (0.44) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL10519457 | 0.90 | RAB9A (0.47) | RAB9ANPC1KMT2AMEN1MAPT | |
| Lysine SCHEMBL10518860 | 0.84 | HDAC6 (0.46) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL10518851 | 0.84 | PARP1 (0.53) | RAB9ANPC1KMT2AMEN1MAPT | |
| Monoethanolamine SCHEMBL10518089 | 0.84 | RAB9A (0.52) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL10517317 | 0.83 | POLB (0.44) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11136424 | 0.82 | MAPT (0.68) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL10517375 | 0.80 | PARP1 (0.46) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL10519229 | 0.76 | KMT2A (0.41) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL10921715 | 0.76 | MAPT (0.72) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190298-B1 | 4-(ISOXAZOLYL)-THIAZOLE-2-OXAMIC ACIDS AND DERIVATIVES THEREOF | ZAMBON S.p.A. (IT) | 1989-10-18 | — | — | EP | disclosed |
| US-4766137-A | 4-(isoxazolyl)-thiazole-2-oxamic acids and derivatives thereof | ZAMBON S.P.A. (IT) | 1988-08-23 | — | — | US | disclosed |