Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15723460 | 1.00 | TDP1 (0.49) | TDP1GABRR1CYP1A2MEN1POLB | |
| SCHEMBL30076415 | 0.86 | TDP1 (0.50) | TDP1MEN1POLBKMT2ACA1 | |
| SCHEMBL3936310 | 0.81 | TDP1 (0.50) | TDP1MEN1POLBKMT2ACA1 | |
| SCHEMBL3936312 | 0.81 | TDP1 (0.50) | TDP1MEN1POLBKMT2ACA1 | |
| SCHEMBL27238622 | 0.80 | CA1 (0.44) | TDP1GABRR1CYP1A2MEN1POLB | |
| SCHEMBL27238624 | 0.80 | CA1 (0.44) | TDP1GABRR1CYP1A2MEN1POLB | |
| SCHEMBL12581244 | 0.80 | CA1 (0.44) | TDP1GABRR1CYP1A2MEN1POLB | |
| SCHEMBL9507515 | 0.77 | GABRR1 (0.42) | TDP1GABRR1CYP1A2BLMACE2 | |
| SCHEMBL25661099 | 0.77 | NOS3 (0.47) | TDP1CYP1A2KMT2ABLMNOS3 | |
| SCHEMBL25660421 | 0.77 | NOS3 (0.47) | TDP1CYP1A2KMT2ABLMNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |