Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509839 | 0.91 | LTA4H (0.42) | GABRR1CYP1A2TDP1BLMACE2 | |
| SCHEMBL9511276 | 0.91 | BLM (0.46) | GABRR1CYP1A2TDP1BLMACE2 | |
| SCHEMBL9509855 | 0.90 | ACE2 (0.42) | GABRR1CYP1A2TDP1BLMACE2 | |
| SCHEMBL9507536 | 0.90 | ACE2 (0.42) | GABRR1CYP1A2TDP1BLMACE2 | |
| SCHEMBL9511234 | 0.78 | TDP1 (0.33) | TDP1MAPT | |
| SCHEMBL10521815 | 0.77 | TDP1 (0.49) | GABRR1CYP1A2TDP1BLMACE2 | |
| SCHEMBL15723460 | 0.77 | TDP1 (0.49) | GABRR1CYP1A2TDP1BLMACE2 | |
| SCHEMBL9779587 | 0.76 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL7230308 | 0.75 | — | — | |
| SCHEMBL170785 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |