Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520284 | 0.88 | GAA (0.61) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2534045 | 0.84 | MAPT (0.69) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10523079 | 0.81 | HSD17B10 (0.58) | POLBMAPTTP53SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10521981 | 0.81 | HSD17B10 (0.58) | POLBMAPTTP53SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10520762 | 0.80 | HTR6 (0.64) | POLBMAPTTP53SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10520461 | 0.80 | HSD17B10 (0.57) | POLBMAPTTP53SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10523102 | 0.80 | HSD17B10 (0.57) | POLBMAPTTP53SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10525312 | 0.79 | HSD17B10 (0.56) | POLBMAPTTP53SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10522484 | 0.79 | HTR6 (0.62) | POLBMAPTTP53SMN1; SMN2HSD17B10 | |
| SCHEMBL10522599 | 0.78 | POLB (0.65) | POLBMAPTTP53SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876267-A | MIGRANES | GLAXO GROUP LIMITED (GB) | 1989-10-24 | — | — | US | disclosed |
| EP-0254433-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1988-01-27 | — | — | EP | disclosed |