SCHEMBL10522003

SCHEMBL10522003

CCCCCC1=Nc2cc(Cl)ccc2S(=O)(=O)N1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.40
CA12 O43570 2/20 0.40
CA4 P22748 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CHEK1 O14757 1/20 0.39
DAPK3 O43293 1/20 0.39
MAP4K4 O95819 1/20 0.39
RET P07949 1/20 0.39
PIM1 P11309 1/20 0.39
LTK P29376 1/20 0.39
GRK5 P34947 1/20 0.39
CSNK1A1 P48729 1/20 0.39
CDK8 P49336 1/20 0.39
PRKX P51817 1/20 0.39
LIMK1 P53667 1/20 0.39
CDK5 Q00535 1/20 0.39
ACVR1 Q04771 1/20 0.39
PTK2 Q05397 1/20 0.39
TYRO3 Q06418 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10524375 0.99 CA12 (0.39) CA2CA12CA4CA7CA9
SCHEMBL10524216 0.85 CA2 (0.43) CA2CA12CA4CA7CA9
SCHEMBL10523787 0.85 CA2 (0.44) CA2CA12CA4CA7CA9
SCHEMBL5624726 0.75 CA1 (0.38) CA2CA12CA4CA7CA9
SCHEMBL10521551 0.74 CHEK1 (0.51) CA2CA12CA4CA7CA9
SCHEMBL10523866 0.73 CA2 (0.48) CA2CA12CA4CA7CA9
SCHEMBL721277 0.72 NPC1 (0.47) MEN1KMT2ASIRT1ABCC8KCNJ11
SCHEMBL9242206 0.72 CA2 (0.36) CA2CA12CA4CA7CA9
SCHEMBL9242215 0.72 RAB9A (0.37) CA2CA12CA4CA7CA9
SCHEMBL9606078 0.71 CHEK1 (0.44) CA2CA12CA4CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO claimed
EP-0327263-A1 Hair growth stimulation with nitroxide and other radicals PROCTOR, Peter H. (US) 1989-08-09 EP disclosed
WO-1988005653-A1 TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS PROCTOR PETER H (US) 1988-08-11 WO disclosed