Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.59 |
| ▸ | ESR1 | P03372 | 10/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8836682 | 0.89 | NR1H2 (0.63) | NR1H2NR1H3MAPT | |
| SCHEMBL10941257 | 0.81 | NR1H2 (0.56) | NR1H2NR1H3MAPTCYP3A4HSD17B10 | |
| SCHEMBL5118101 | 0.80 | NR1H2 (0.56) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL9651811 | 0.80 | NR1H2 (0.56) | NR1H2NR1H3MAPTHPGD | |
| SCHEMBL7738428 | 0.79 | NR1H2 (0.54) | NR1H2NR1H3 | |
| SCHEMBL7737525 | 0.79 | NR1H2 (0.54) | NR1H2NR1H3MAPTALDH1A1NPC1 | |
| SCHEMBL9651763 | 0.79 | NR1H2 (0.54) | NR1H2NR1H3ALDH1A1TSHR | |
| SCHEMBL1147728 | 0.78 | NR1H2 (0.53) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL1219525 | 0.78 | ESR1 (0.41) | NR1H2NR1H3ESR1ESR2MAPT | |
| SCHEMBL7739084 | 0.77 | NR1H2 (0.53) | NR1H2NR1H3MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804612-A | PLASMA DRY-ETCHING RESISTANCE | TOKYO OHKA KOGYO CO., LTD. (JP) | 1989-02-14 | — | — | US | claimed |
| US-4804612-A | PLASMA DRY-ETCHING RESISTANCE | TOKYO OHKA KOGYO CO., LTD. (JP) | 1989-02-14 | — | — | US | disclosed |