SCHEMBL1147728

SCHEMBL1147728

C=CC[Si](C)(C)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.53
NR1H3 Q13133 2/20 0.53
MAPT P10636 2/20 0.44
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MGAM O43451 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
MMP9 P14780 2/20 0.31
CYP2C19 P33261 1/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8836682 0.88 NR1H2 (0.63) NR1H2NR1H3MAPT
SCHEMBL2290391 0.83 NR1H2 (0.42) NR1H2NR1H3MAPTESR1ESR2
SCHEMBL3317837 0.82 NR1H2 (0.37) NR1H2NR1H3MAPTESR1ESR2
SCHEMBL9862805 0.82 NR1H2 (0.37) NR1H2NR1H3MAPTESR1ESR2
SCHEMBL10941257 0.80 NR1H2 (0.56) NR1H2NR1H3MAPTALDH1A1MMP9
SCHEMBL17292829 0.78 NR1H2 (0.35) NR1H2NR1H3MAPTESR1ESR2
SCHEMBL8937181 0.78 ESR1 (0.47) NR1H2NR1H3MAPTESR1ESR2
SCHEMBL15302676 0.78 NR1H2 (0.39) NR1H2NR1H3MAPTESR1ESR2
SCHEMBL9651763 0.78 NR1H2 (0.54) NR1H2NR1H3TSHRALDH1A1
SCHEMBL15863779 0.78 NR1H2 (0.50) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110305457-A Preparation method of transparent toughened polylactic acid material 杭州卓普新材料科技有限公司 2019-10-08 CN claimed
EP-3224330-B1 INTERNAL POLYMERIC BREAKER FOR VISCOELASTIC SURFACTANT-BASED FLUIDS AKZO NOBEL CHEMICALS INT BV (NL) 2019-02-20 EP claimed
US-10017683-B2 Internal polymeric breaker for viscoelastic surfactant-based fluids AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2018-07-10 US claimed
US-20170313929-A1 Internal Polymeric Breaker for Viscoelastic Surfactant-Based Fluids AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2017-11-02 US claimed
EP-3224330-A1 INTERNAL POLYMERIC BREAKER FOR VISCOELASTIC SURFACTANT-BASED FLUIDS Akzo Nobel Chemicals International B.V. (NL) 2017-10-04 EP claimed
WO-2016083318-A1 INTERNAL POLYMERIC BREAKER FOR VISCOELASTIC SURFACTANT-BASED FLUIDS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-06-02 WO claimed
US-8580143-B2 Lyotropic chromonic liquid crystal composition, method for manufacture of lyotropic chromonic liquid crystal coating film, and lyotropic chromonic liquid crystal coating film manufactured thereby KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2013-11-12 US claimed
EP-1988873-B1 POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME LUBRIZOL ADVANCED MAT INC (US) 2013-01-09 EP claimed
US-8021650-B2 Polymers containing silicone copolyol macromers and personal care compositions containing same LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-09-20 US claimed
EP-1988873-A2 POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME Lubrizol Advanced Materials, Inc. (US) 2008-11-12 EP claimed
WO-2007101059-A2 POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME LUBRIZOL ADVANCED MATERIALS, INC. (US) 2007-09-07 WO claimed
US-20070202069-A1 Polymers Containing Silicone Copolyol Macromers and Personal Care Compositions Containing Same LUBRIZOL ADVANCED MATERIALS, INC. 2007-08-30 US claimed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 US claimed
US-20250109362-A1 A LAUNDRY SCENTING FORMULATION DOW SILICONES CORPORATION 2025-04-03 US disclosed
CN-114341215-B Curable composition 株式会社日本触媒 2024-12-27 CN disclosed
EP-4469548-A1 A LAUNDRY SCENTING FORMULATION Dow Silicones Corporation (US) 2024-12-04 EP disclosed
EP-0041839-A1 Ultrathin solid membrane composed of silicon-containing copolymer, process for producing said membrane and use thereof for concentrating a gas TEIJIN LIMITED (JP) 1981-12-16 EP disclosed
US-4064193-A Heat-resistant polymers based on polyamines and oligomers possessing imide groups with unsaturated polyester RHONE-POULENC S.A. (FR) 1977-12-20 US disclosed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 US disclosed
US-4005154-A Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups RHONE-POULENC S.A. (FR) 1977-01-25 US disclosed