Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790937 | 0.88 | ACHE (0.38) | HPGDTSHRACHELMNA | |
| SCHEMBL10521030 | 0.83 | HPGD (0.38) | HPGDPTK2BRXFP1TSHRACHE | |
| SCHEMBL10523410 | 0.80 | ESR1 (0.42) | HPGDPTK2BRXFP1TSHRACHE | |
| SCHEMBL10523774 | 0.78 | HPGD (0.55) | HPGDTSHRACHELMNAALOX12 | |
| SCHEMBL10523760 | 0.76 | ACHE (0.46) | HPGDPTK2BRXFP1TSHRACHE | |
| SCHEMBL10523275 | 0.73 | TSHR (0.45) | HPGDTSHRACHELMNAALOX12 | |
| SCHEMBL7891692 | 0.71 | TSHR (0.47) | HPGDTSHRACHELMNAALOX12 | |
| SCHEMBL10523337 | 0.70 | NPSR1 (0.44) | TSHRACHELMNAALOX12 | |
| SCHEMBL10803194 | 0.70 | ESR1 (0.43) | TSHRACHELMNAALOX12 | |
| SCHEMBL30442840 | 0.69 | MEN1 (0.44) | HPGDLMNATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806691-A | Process for the preparation of tertiary phosphine oxides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |