Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522880 | 0.94 | ACHE (0.38) | ACHELMNATOP1POLBTSHR | |
| SCHEMBL10521030 | 0.91 | HPGD (0.38) | ACHELMNAHPGDPOLBTSHR | |
| SCHEMBL10523410 | 0.87 | ESR1 (0.42) | ACHELMNAHPGDPOLBTSHR | |
| SCHEMBL10520398 | 0.86 | ACHE (0.46) | ACHENFE2L2LMNAHPGDTOP1 | |
| SCHEMBL10522932 | 0.80 | ACHE (0.65) | ACHENFE2L2LMNAHPGDPTGS1 | |
| SCHEMBL10521020 | 0.80 | ACHE (0.65) | ACHENFE2L2LMNAHPGDPTGS1 | |
| SCHEMBL10523337 | 0.78 | NPSR1 (0.44) | ACHELMNATSHRNPSR1ALDH1A1 | |
| SCHEMBL7891692 | 0.76 | TSHR (0.47) | ACHELMNAHPGDTSHRALDH1A1 | |
| SCHEMBL10522221 | 0.76 | HPGD (0.40) | ACHELMNAHPGDTSHRPTK2B | |
| SCHEMBL10523748 | 0.75 | ESR1 (0.35) | ACHENFE2L2LMNATOP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806691-A | Process for the preparation of tertiary phosphine oxides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| US-4675446-A | OXIDATION OF PHOSPHINE SULFIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-23 | — | — | US | disclosed |