Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748722 | 0.84 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2MAOA | |
| SCHEMBL9129787 | 0.79 | MEN1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10518699 | 0.79 | METAP2 (0.61) | METAP2 | |
| SCHEMBL162827 | 0.77 | MAPT (0.54) | MAPTMEN1KMT2ASMN1; SMN2MAOA | |
| SCHEMBL14357551 | 0.77 | ALDH1A1 (0.56) | MAPTMEN1KMT2ASMN1; SMN2MAOA | |
| SCHEMBL29643318 | 0.77 | ALDH1A1 (0.56) | MAPTMEN1KMT2ASMN1; SMN2MAOA | |
| SCHEMBL7757842 | 0.77 | KDM4E (0.59) | MAPTMEN1KMT2ASMN1; SMN2MAOA | |
| SCHEMBL5230905 | 0.77 | HPGD (0.56) | MAPTMEN1KMT2ASMN1; SMN2MAOA | |
| SCHEMBL6420811 | 0.76 | GAA (0.63) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL14036493 | 0.76 | MAPT (0.57) | MAPTMEN1KMT2ASMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873350-A | Diselenobis-benzoic acid amides of primary and secondary amines and processes for the treatment of diseases in humans caused by a cell injury | A NATTERMANN & CIE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0198277-B1 | DISELENO-BIS-BENZAMIDES OF PRIMARY AND SECONDARY AMINES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | A. Nattermann & Cie. GmbH (DE) | 1989-05-03 | — | — | EP | disclosed |
| EP-0198277-A1 | Diseleno-bis-benzamides of primary and secondary amines, processes for their production and pharmaceutical preparations containing them | A. Nattermann & Cie. GmbH (DE) | 1986-10-22 | — | — | EP | disclosed |