Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1052302 | 0.94 | CES2 (0.41) | CES2CES1CHRM1CHRM3CHRM4 | |
| Bicarbonate SCHEMBL21957729 | 0.92 | CES2 (0.43) | CES2CES1CHRM1CHRM3CHRM4 | |
| Acetic Acid SCHEMBL7530111 | 0.90 | CES2 (0.41) | CES2CES1CHRM1CHRM3CHRM4 | |
| Oxalic Acid SCHEMBL1052304 | 0.90 | CHRM1 (0.42) | CES2CES1CHRM1CHRM3CHRM4 | |
| Propionic Acid SCHEMBL21957786 | 0.88 | CES2 (0.44) | CES2CES1CHRM1CHRM3CHRM4 | |
| Bicarbonate SCHEMBL21957730 | 0.87 | CHRM1 (0.43) | CES2CES1CHRM1CHRM3CHRM4 | |
| Malonic Acid SCHEMBL21957699 | 0.86 | CES1 (0.39) | CES2CES1CHRM1CHRM3CHRM4 | |
| Fumaric Acid SCHEMBL21957712 | 0.85 | CES2 (0.38) | CES2CES1CHRM1CHRM3CHRM4 | |
| Fumaric Acid SCHEMBL21957765 | 0.85 | CES2 (0.38) | CES2CES1CHRM1CHRM3CHRM4 | |
| Terephthalic Acid SCHEMBL21957720 | 0.85 | CA2 (0.52) | CES2CES1LMNACA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867471-B2 | Process for preparing advanced ceramic powders using onium dicarboxylates | SACHEM, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090250850-A1 | PROCESS FOR PREPARING ADVANCED CERAMIC POWDERS USING ONIUM DICARBOXYLATES | SACHEM, INC. | 2009-10-08 | — | — | US | disclosed |