SCHEMBL1052309

SCHEMBL1052309

C#Cc1ccc2c3ccc(C#C)cc3n(CC)c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
MAPT P10636 3/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 2/20 0.39
KMT2A Q03164 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPK1 P28482 1/20 0.39
HBB P68871 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM1A O60341 1/20 0.36
PTGER4 P35408 1/20 0.35
RORC P51449 3/20 0.35
LMNA P02545 2/20 0.34
TSHR P16473 1/20 0.34
DYRK1A Q13627 1/20 0.34
HTR7 P34969 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.33
SRC P12931 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1049148 0.85 KDM4E (0.46) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL1052731 0.81 MAPT (0.59) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL21076085 0.81 PTGER4 (0.48) PTGER4RORCSRC
SCHEMBL21599721 0.74 PTGER4 (0.59) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL24463411 0.73 KDM4E (0.59) KDM4EHPGDHTTKMT2ATDP1
SCHEMBL12548590 0.71 KDM4E (0.43) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL13451234 0.70 GPR3 (0.57) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL29556340 0.69 MAPT (0.44) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL19056399 0.69 MAPT (0.44) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL4892851 0.69 KDM4E (0.65) KDM4EALDH1A1HPGDMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7875748-B2 Prepared by reaction of tetraphenylcyclopentadienone with 1,4-diethynyl-2,5-dimethoxybenzene; can be used as a core material for an organic electroluminescence element or other optical devices KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2011-01-25 US disclosed
US-20090240062-A1 COMPOUND DERIVED FROM CYCLOPENTADIENONE, PREPARATION METHOD THEREOF AND EL ELEMENT USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-09-24 US disclosed
US-20050067955-A1 Compound derived from cyclopentadienone, preparation method thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240062-A1 COMPOUND DERIVED FROM CYCLOPENTADIENONE, PREPARATION METHOD THEREOF AND EL ELEMENT USING THE SAME ELP1, CYP51A1, ELOVL1 KDM4E 1785/4885ALDH1A1 525/4885HPGD 212/4885
US-20050067955-A1 Compound derived from cyclopentadienone, preparation method thereof and EL element using the same ELP1, CYP51A1, ELOVL1 KDM4E 1785/4885ALDH1A1 525/4885HPGD 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.