SCHEMBL10523402

SCHEMBL10523402

CC(=O)CC(C(=O)O)C(CCC(=O)O)C(C)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
CYP1A2 P05177 2/20 0.43
FOLH1 Q04609 7/20 0.42
TET2 Q6N021 3/20 0.40
KDM4A O75164 2/20 0.40
KDM4C Q9H3R0 2/20 0.40
KDM2A Q9Y2K7 2/20 0.40
TET3 O43151 1/20 0.40
LMNA P02545 1/20 0.39
SLC15A2 Q16348 1/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9845052 0.82 CYP1A2 (0.45) TDP1CYP1A2FOLH1TET2KDM4A
SCHEMBL17637931 0.81 TDP1 (0.64) TDP1FOLH1LMNASLC15A2SLC1A3
SCHEMBL17637932 0.80 TDP1 (0.58) TDP1LMNASLC15A2GRIK1SLC1A3
SCHEMBL27595421 0.78 FOLH1 (0.41) TDP1CYP1A2FOLH1TET2KDM4A
SCHEMBL15249460 0.78 TDP1 (0.74) TDP1FOLH1LMNASLC15A2SLC1A3
SCHEMBL578994 0.76 TDP1 (0.70) TDP1CYP1A2FOLH1TET2KDM4A
SCHEMBL4604947 0.75 TDP1 (0.42) TDP1CYP1A2FOLH1KDM2ALMNA
SCHEMBL9323880 0.75 CYP1A2 (0.52) CYP1A2FOLH1TET2KDM4AKDM4C
SCHEMBL13726724 0.75 TET2 (0.57) TDP1CYP1A2FOLH1TET2KDM4A
SCHEMBL11584000 0.74 GABRP (0.50) CYP1A2FOLH1TET2KDM4AKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161655-B1 LIGHT-SENSITIVE COMPOSITION AND TWO-COMPONENT DIAZOTYPE MATERIAL PREPARED THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-04 EP disclosed
EP-0161655-A2 Light-sensitive composition and two-component diazotype material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-21 EP disclosed
EP-0056227-A1 Two-component diazotype material HOECHST AKTIENGESELLSCHAFT (DE) 1982-07-21 EP disclosed
EP-0017699-B1 DERIVATIVES OF 2-HYDROXY-NAPHTHALENE AND DIAZO PHOTOGRAPHIC MATERIAL CONTAINING THEM AS COUPLING COMPONENTS HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-16 EP disclosed
EP-0017699-A1 Derivatives of 2-hydroxy-naphthalene and diazo photographic material containing them as coupling components HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-29 EP disclosed