Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13365248 | 0.83 | TDP1 (0.58) | TDP1LMNASLC15A2ALDH1A1SLC22A6 | |
| SCHEMBL17637931 | 0.76 | TDP1 (0.64) | TDP1LMNASLC15A2ALDH1A1FOLH1 | |
| SCHEMBL10523402 | 0.75 | TDP1 (0.44) | TDP1LMNASLC15A2FOLH1GABRP | |
| SCHEMBL13332621 | 0.75 | TDP1 (0.48) | TDP1SLC22A6GPR84SMN1; SMN2ALOX15 | |
| SCHEMBL2343722 | 0.73 | LMNA (0.46) | TDP1LMNASLC15A2ALDH1A1FOLH1 | |
| SCHEMBL1237039 | 0.72 | GABRP (0.45) | TDP1LMNASLC15A2ALDH1A1FOLH1 | |
| SCHEMBL25682825 | 0.72 | TDP1 (0.50) | TDP1LMNAALDH1A1SLC22A6SMN1; SMN2 | |
| SCHEMBL15305176 | 0.71 | FOLH1 (0.71) | TDP1LMNASLC15A2FOLH1 | |
| SCHEMBL12993346 | 0.71 | FOLH1 (0.71) | TDP1LMNASLC15A2FOLH1 | |
| SCHEMBL3698857 | 0.71 | FOLH1 (0.71) | TDP1LMNASLC15A2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1947082-A2 | Oximes or imines of 4-pentulosonic acid methyl esters as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947084-A2 | 2-Pyrrolidones as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1305284-A4 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2005-08-03 | — | — | EP | disclosed |
| US-6583297-B2 | From tri-O-acetyl-D-erythro-4-pentulosonic acid esters | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2003-06-24 | — | — | US | disclosed |
| EP-1305284-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6518437-B1 | 2,3,5-Tri-O-acetyl-1,4-Dideoxy-1,4-imino-D-ribitol. for chemical intermediates | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-02-11 | — | — | US | disclosed |
| US-6492534-B2 | CHEMICAL INTERMEDIATE FOR BIOSYNTHESIS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6482974-B2 | FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-11-19 | — | — | US | disclosed |
| US-6482973-B2 | FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-11-19 | — | — | US | disclosed |
| US-6423867-B1 | FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-07-23 | — | — | US | disclosed |
| US-6414163-B1 | PREPARING 1,4-DIDEOXY-1,4-IMINOPENTITOL BY REDUCTIVE CYCLIZATION OF SPECIFIED OXIME OR IMINE WITH REDUCING AGENT WHICH IS SOURCE OF SINGLET HYDROGEN OR HYDRIDE VIA INTERMEDIATE PYRROLIDONE LACTAM | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-07-02 | — | — | US | disclosed |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2002-02-28 | — | — | US | disclosed |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERS | 2002-02-28 | — | — | US | disclosed |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING | 2002-02-14 | — | — | US | disclosed |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-14 | — | — | US | disclosed |
| WO-2002010130-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885LMNA 2986/4885SLC15A2 4263/4885 |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885LMNA 2986/4885SLC15A2 4263/4885 |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885LMNA 2986/4885SLC15A2 4263/4885 |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885LMNA 2986/4885SLC15A2 4263/4885 |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885LMNA 2986/4885SLC15A2 4263/4885 |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885LMNA 2986/4885SLC15A2 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.