Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | MECP2 | P51608 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745017 | 0.90 | MECP2 (0.46) | MECP2MAOAMAP4K4MEN1PSIP1 | |
| SCHEMBL1646929 | 0.88 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL10520530 | 0.84 | KCNH2 (0.38) | NOS3NOS1NOS2SMN1; SMN2 | |
| SCHEMBL1338582 | 0.80 | CHRNB4 (0.53) | ALDH1A1MAPTHPGDKMT2APOLB | |
| SCHEMBL23054974 | 0.79 | KCNH2 (0.37) | — | |
| SCHEMBL14320600 | 0.79 | NOS3 (0.47) | NOS3NOS1NOS2MEN1KDM4E | |
| SCHEMBL9319771 | 0.78 | CHRNB4 (0.44) | NOS3NOS1NOS2ALDH1A1LMNA | |
| SCHEMBL105809 | 0.76 | NPC1 (0.41) | SMN1; SMN2 | |
| SCHEMBL1645947 | 0.76 | NOS3 (0.44) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL12567710 | 0.73 | NISCH (0.45) | MEN1KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824843-A | Substituted amide inhibitors of cholesterol absorption | WARNER-LAMBERT COMPANY (US) | 1989-04-25 | — | — | US | disclosed |