Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305973 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTMMP8TSHRMEN1 | |
| SCHEMBL9530414 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTMMP8TDP1LMNA | |
| SCHEMBL1421006 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTTSHRMEN1KMT2A | |
| SCHEMBL3507308 | 0.85 | TSHR (0.50) | SMN1; SMN2MAPTTSHRMEN1KMT2A | |
| SCHEMBL27492502 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMMP8TSHRMEN1 | |
| SCHEMBL7437317 | 0.85 | ALDH1A1 (0.50) | SMN1; SMN2TSHRKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7265343 | 0.84 | TSHR (0.54) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2340596 | 0.83 | MMP8 (0.58) | SMN1; SMN2MAPTMMP8TSHRMEN1 | |
| SCHEMBL18065697 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTMMP8TSHRMEN1 | |
| SCHEMBL935980 | 0.83 | TDP1 (0.59) | SMN1; SMN2MAPTMMP8TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1121297-A | — | — | None | — | — | JP | disclosed |
| JP-H01121297-A | PRODUCTION OF N-SUBSTITUTED-AMINO ACID DERIVATIVE | SAGAMI CHEM RES CENTER | 1989-05-12 | — | — | JP | disclosed |