Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732745 | 0.67 | TLR8 (0.36) | LMNA | |
| SCHEMBL6555162 | 0.64 | POLB (0.38) | LMNA | |
| SCHEMBL4619452 | 0.64 | ALDH1A1 (0.36) | — | |
| SCHEMBL718616 | 0.62 | TP53 (0.41) | LMNA | |
| SCHEMBL8509078 | 0.61 | — | — | |
| SCHEMBL805463 | 0.59 | NPC1 (0.45) | LMNA | |
| SCHEMBL8879771 | 0.58 | GAA (0.51) | LMNA | |
| SCHEMBL1666032 | 0.58 | — | — | |
| SCHEMBL22079381 | 0.58 | — | — | |
| SCHEMBL9797864 | 0.58 | KDM4E (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839355-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0309789-A1 | 4-Oxo-3-quinolinecarboxylic acids useful as antibacterial agents and preparation thereof | STERLING WINTHROP INC. (US) | 1989-04-05 | — | — | EP | disclosed |
| EP-0306860-A2 | 4-Oxo-3-Quinolinecarboxylic acids useful as antibacterial agents and preparation thereof | STERLING WINTHROP INC. (US) | 1989-03-15 | — | — | EP | disclosed |