SCHEMBL718616

SCHEMBL718616

C=Cc1cc(C)nc(C)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.37
POLB P06746 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
HDAC8 Q9BY41 2/20 0.33
NOS3 P29474 2/20 0.33
NOS2 P35228 2/20 0.33
TSHR P16473 1/20 0.33
NOS1 P29475 1/20 0.33
GRM5 P41594 1/20 0.32
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GRM4 Q14833 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9170444 0.85 TP53 (0.35) TP53TDP1ALDH1A1LMNAPOLB
SCHEMBL29697288 0.84 LMNA (0.37) TP53TDP1ALDH1A1LMNAPOLB
SCHEMBL22990718 0.84 LMNA (0.37) TP53TDP1ALDH1A1LMNAPOLB
SCHEMBL18266141 0.84 NOS2 (0.52) TP53TDP1NOS3NOS2NOS1
SCHEMBL26768907 0.80 TP53 (0.36) TP53TDP1HDAC8NOS3NOS2
SCHEMBL12587952 0.77 ALDH1A1 (0.46) TP53TDP1ALDH1A1HDAC8TSHR
SCHEMBL20888240 0.73 KDM4E (0.42) TP53ALDH1A1LMNAPOLBHPGD
SCHEMBL24737339 0.72 LMNA (0.42) TP53TDP1ALDH1A1LMNAPOLB
SCHEMBL378339 0.72 SRC (0.42) ALDH1A1LMNAPOLBAPOBEC3GNOS3
SCHEMBL27244170 0.72 LMNA (0.37) ALDH1A1LMNAPOLBAPOBEC3GNOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114877069-B Metal-coated gasket filled with modified ceramic fibers and preparation method thereof 慈溪埃弗龙密封件有限公司 2025-01-28 CN claimed
US-20240425373-A1 Fabrication Of Micro-Structured Carbon Materials With Bicontinuous Pores Via Pyrolysis Of Polymerized Bijels THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2024-12-26 US claimed
CN-114621557-B Composite material based on modified polyether-ether-ketone and preparation method thereof 宁波中科甬建新材料科技有限公司 2024-05-07 CN claimed
CN-114877069-A Modified ceramic fiber filled metal-coated gasket and preparation method thereof 慈溪埃弗龙密封件有限公司 2022-08-09 CN claimed
CN-114621557-A Composite material based on modified polyether-ether-ketone and preparation method thereof 宁波中科甬建新材料科技有限公司 2022-06-14 CN claimed
US-20120049167-A1 ORGANIC ELECTROLUMINESCENT DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US claimed
EP-2383814-A1 ORGANIC ELECTROLUMINESCENT DEVICE Sumitomo Chemical Company, Limited (JP) 2011-11-02 EP claimed
CN-114877069-B Metal-coated gasket filled with modified ceramic fibers and preparation method thereof 慈溪埃弗龙密封件有限公司 2025-01-28 CN disclosed
US-20240425373-A1 Fabrication Of Micro-Structured Carbon Materials With Bicontinuous Pores Via Pyrolysis Of Polymerized Bijels THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2024-12-26 US disclosed
CN-114621557-B Composite material based on modified polyether-ether-ketone and preparation method thereof 宁波中科甬建新材料科技有限公司 2024-05-07 CN disclosed
CN-114877069-A Modified ceramic fiber filled metal-coated gasket and preparation method thereof 慈溪埃弗龙密封件有限公司 2022-08-09 CN disclosed
CN-114621557-A Composite material based on modified polyether-ether-ketone and preparation method thereof 宁波中科甬建新材料科技有限公司 2022-06-14 CN disclosed
US-11332566-B2 Polymers, methods for preparing same, and uses thereof particularly for metal capture Universite Paris-Saclay (FR) 2022-05-17 US disclosed
US-5397445-A Bipolar membrane, improved current efficiency ASAHI GLASS COMPANY LTD. (JP) 1995-03-14 US disclosed
EP-0531999-A1 Method for producing an acid and/or alkali metal hydroxide ASAHI GLASS COMPANY LTD. (JP) 1993-03-17 EP disclosed
EP-0095269-B1 RADIATION-SENSITIVE COMPOSITIONS OF POLYMERS CONTAINING A PI-METAL CARBONYL COMPLEX OF CONJUGATED POLYOLEFIN MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-02-24 EP disclosed
US-4503140-A Radiation-sensitive compositions of polymers containing a π-metal carbonyl complex of conjugated polyolefin MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-05 US disclosed
EP-0095269-A2 Radiation-sensitive compositions of polymers containing a pi-metal carbonyl complex of conjugated polyolefin MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-11-30 EP disclosed
US-4260552-A INSECTICIDES, HERBICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed