Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521853 | 0.88 | SMN1; SMN2 (0.36) | PSMB8PSMB5SMN1; SMN2ANPEPCTSS | |
| SCHEMBL10522976 | 0.82 | ANPEP (0.40) | PSMB8PSMB5MMP9MMP8MMP14 | |
| SCHEMBL10750427 | 0.78 | HRH4 (0.45) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL10519260 | 0.77 | GAA (0.38) | HRH4PIN1MMEACECPA1 | |
| SCHEMBL10570975 | 0.75 | HRH4 (0.47) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL10570967 | 0.75 | HRH4 (0.47) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL10751443 | 0.74 | HRH4 (0.45) | HRH4MMEACECPA1ACE2 | |
| SCHEMBL8481892 | 0.74 | HRH4 (0.56) | HRH4PIN1MMEACECPA1 | |
| SCHEMBL8481399 | 0.74 | HRH4 (0.56) | HRH4PIN1MMEACECPA1 | |
| SCHEMBL8481408 | 0.74 | HRH4 (0.56) | HRH4PIN1MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863904-A | Dipeptides as renin inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |