Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880872 | 0.88 | TRPV1 (0.41) | TRPV1DRD2KMT2ADRD3ALDH1A1 | |
| SCHEMBL10524343 | 0.84 | TRPV1 (0.42) | TRPV1DRD2KMT2AALDH1A1PTGS2 | |
| SCHEMBL10526177 | 0.82 | ALDH1A1 (0.40) | TRPV1DRD2KMT2AALDH1A1PTGS2 | |
| SCHEMBL10526688 | 0.81 | TRPV1 (0.41) | TRPV1DRD2KMT2AALDH1A1PTGS2 | |
| SCHEMBL10525350 | 0.81 | TRPV1 (0.41) | TRPV1DRD2KMT2AALDH1A1PTGS2 | |
| SCHEMBL8686345 | 0.81 | TRPV1 (0.50) | TRPV1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10526130 | 0.79 | DRD4 (0.39) | TRPV1DRD2KMT2AALDH1A1PTGS2 | |
| SCHEMBL10527805 | 0.77 | ALDH1A1 (0.41) | TRPV1KMT2AALDH1A1PTGS2KDM4E | |
| SCHEMBL10526367 | 0.76 | TRPV1 (0.40) | TRPV1DRD2KMT2ADRD3KCNA5 | |
| SCHEMBL11832981 | 0.74 | TRPV1 (0.51) | TRPV1KMT2AALDH1A1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188803-B1 | PIPERAZINE DERIVATIVE | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |
| EP-0188803-A1 | Piperazine derivative | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1986-07-30 | — | — | EP | disclosed |