Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832981 | 0.84 | TRPV1 (0.51) | TRPV1PDGFRBFGFR1KDRAKR1C2 | |
| SCHEMBL10524712 | 0.81 | TRPV1 (0.42) | TRPV1ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL10880872 | 0.80 | TRPV1 (0.41) | TRPV1ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL11189245 | 0.79 | TRPV1 (0.45) | TRPV1AKR1C2ALDH1A1MAPTRAB9A | |
| SCHEMBL8122137 | 0.79 | TRPV1 (0.45) | TRPV1AKR1C2ALDH1A1MAPTRAB9A | |
| SCHEMBL8796396 | 0.78 | TRPV1 (0.46) | TRPV1PDGFRBFGFR1KDRAKR1C2 | |
| SCHEMBL11557313 | 0.78 | TRPV1 (0.45) | TRPV1AKR1C2ALDH1A1MAPTRAB9A | |
| SCHEMBL8031503 | 0.76 | TRPV1 (0.43) | TRPV1AKR1C2ALDH1A1MAPTRAB9A | |
| SCHEMBL4562595 | 0.76 | AKR1C2 (0.48) | TRPV1PDGFRBFGFR1KDRAKR1C2 | |
| SCHEMBL9359811 | 0.75 | AKR1C2 (0.62) | AKR1C2MAPTRAB9AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776962-A | Lactone compounds for treating patient with precancerous lesions | CELL PATHWAYS, INC. (US) | 1998-07-07 | — | — | US | disclosed |