Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524465 | 0.92 | ABCB11 (0.40) | ABCB11KMT2AALOX15GSK3B | |
| SCHEMBL10524715 | 0.85 | ABCB11 (0.39) | ABCB11GAAKDM4EALDH1A1GLA | |
| SCHEMBL10525051 | 0.83 | ABCB11 (0.64) | ABCB11GAAKDM4EALDH1A1KMT2A | |
| SCHEMBL10522819 | 0.83 | ABCB11 (0.46) | ABCB11GAAKDM4EALDH1A1GLA | |
| SCHEMBL29371382 | 0.82 | ABCB11 (0.50) | ABCB11GAAKDM4EALDH1A1GLA | |
| SCHEMBL10523119 | 0.80 | ABCB11 (0.46) | ABCB11KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL10523376 | 0.78 | ABCB11 (0.38) | ABCB11GAAKDM4EALDH1A1GLA | |
| SCHEMBL10524461 | 0.78 | KMT2A (0.36) | ABCB11KMT2AALOX15GSK3B | |
| SCHEMBL9643611 | 0.77 | ABCB11 (0.49) | ABCB11GAAKDM4EALDH1A1GLA | |
| SCHEMBL10522294 | 0.76 | ABCB11 (0.42) | ABCB11GAAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840965-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1989-06-20 | — | — | US | claimed |
| US-4840965-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1989-06-20 | — | — | US | disclosed |