Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522283 | 0.92 | ABCB11 (0.42) | ABCB11MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL29372079 | 0.84 | ABCB11 (0.49) | ABCB11MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL10525051 | 0.81 | ABCB11 (0.64) | ABCB11MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL9643565 | 0.80 | ABCB11 (0.67) | ABCB11MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL9643247 | 0.78 | ABCB11 (0.47) | ABCB11MAPTLMNAGAAPOLB | |
| SCHEMBL10502679 | 0.77 | ABCB11 (0.46) | ABCB11MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL10523119 | 0.77 | ABCB11 (0.46) | ABCB11SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL10524179 | 0.77 | ABCB11 (0.37) | ABCB11MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL10503448 | 0.76 | MAPT (0.43) | ABCB11MAPTLMNAGAAPOLB | |
| SCHEMBL10524720 | 0.76 | ABCB11 (0.45) | ABCB11HTTGAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840965-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1989-06-20 | — | — | US | disclosed |