Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526001 | 0.90 | THRB (0.47) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL238596 | 0.83 | THRB (0.44) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL10524830 | 0.83 | THRB (0.34) | THRBTSHRHPGDTDP1 | |
| SCHEMBL15405613 | 0.83 | THRB (0.48) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL10526534 | 0.81 | POLB (0.43) | THRBTSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4661265 | 0.80 | THRB (0.50) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL15901529 | 0.79 | THRB (0.55) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL10526007 | 0.79 | THRB (0.44) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL3169558 | 0.78 | THRB (0.53) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL28846555 | 0.78 | THRB (0.59) | THRBTSHRALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886852-A | PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION | KANSAI PAINT COMPANY, LIMITED (JP) | 1989-12-12 | — | — | US | claimed |
| US-4886852-A | PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION | KANSAI PAINT COMPANY, LIMITED (JP) | 1989-12-12 | — | — | US | disclosed |