Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101734 | 0.83 | HCAR2 (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9AHCAR2 | |
| SCHEMBL6441199 | 0.81 | MAPT (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9AHCAR2 | |
| SCHEMBL15405613 | 0.81 | THRB (0.48) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL3913243 | 0.81 | THRB (0.55) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL10524732 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL10526001 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL15901529 | 0.79 | THRB (0.55) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL3101738 | 0.79 | TDP1 (0.46) | THRBTSHRALDH1A1HPGDTDP1 | |
| SCHEMBL24709495 | 0.77 | THRB (0.60) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL10526007 | 0.77 | THRB (0.44) | THRBTSHRALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947393-B2 | Coating agent | NIPPON SODA CO., LTD. (JP) | 2021-03-16 | — | — | US | disclosed |
| EP-2949716-B1 | COATING AGENT | NIPPON SODA CO (JP) | 2020-04-29 | — | — | EP | disclosed |
| US-20150353738-A1 | COATING AGENT | NIPPON SODA CO., LTD. (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2949716-A1 | COATING AGENT | Nippon Soda Co., Ltd. (JP) | 2015-12-02 | — | — | EP | disclosed |
| EP-1444239-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB (US) | 2008-12-24 | — | — | EP | disclosed |
| US-7132494-B2 | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2006-11-07 | — | — | US | disclosed |
| US-6881809-B2 | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2005-04-19 | — | — | US | disclosed |
| US-6846897-B2 | High refractive index aromatic-based silyl monomers | BAUSCH AND LOMB, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040230023-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C (US) | 2004-11-18 | — | — | US | disclosed |
| US-20040215156-A1 | High refractive index aromatic-based silyl monomers | SOLTA MEDICAL, INC. | 2004-10-28 | — | — | US | disclosed |
| US-20040215032-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C | 2004-10-28 | — | — | US | disclosed |
| US-20040210023-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C (US) | 2004-10-21 | — | — | US | disclosed |
| EP-1444239-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-11 | — | — | EP | disclosed |
| US-6762271-B2 | INTRAOCULAR LENSES, CONTACT LENSES AND CORNEAL INLAYS | BAUSCH & LOMB INCORPORATED | 2004-07-13 | — | — | US | disclosed |
| US-20030105255-A1 | High refractive index aromatic-based silyl monomers | BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC. (CA) | 2003-06-05 | — | — | US | disclosed |
| WO-2003040152-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353738-A1 | COATING AGENT | ITGA1, ITGA2, L1CAM | THRB 3589/4885TSHR 3363/4885ALDH1A1 708/4885 |
| US-20040215032-A1 | High refractive index aromatic-based silyl monomers | SMAD2, SMAD3, FHIT | THRB 4416/4885TSHR 4336/4885ALDH1A1 3491/4885 |
| US-10947393-B2 | Coating agent | ITGA1, ITGA2, L1CAM | THRB 3589/4885TSHR 3363/4885ALDH1A1 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.