Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.43 |
| ▸ | CDC25B | P30305 | 8/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.43 |
| ▸ | GJB2 | P29033 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524772 | 0.90 | SSTR1 (0.46) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL8429515 | 0.89 | TACR1 (0.50) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL8653090 | 0.87 | GJB2 (0.52) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL8655411 | 0.87 | GJB2 (0.52) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL1961043 | 0.84 | GJB2 (0.45) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL1780241 | 0.84 | GJB2 (0.45) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL10524731 | 0.83 | SSTR1 (0.57) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL10524725 | 0.83 | SSTR1 (0.57) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL8653092 | 0.83 | SSTR1 (0.57) | PTPN1CDC25BPTPN2PTPN6PTPN11 | |
| SCHEMBL8429519 | 0.83 | SSTR1 (0.57) | PTPN1CDC25BPTPN2PTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871837-A | DEPROTECTING SILYL-PROTECTED CARBOHYDRATES, AMINO ACIDS, PEPTIDES; LEWIS ACID HYDROLYSIS | SYMBICOM AKTIEBOLAG (SE) | 1989-10-03 | — | — | US | disclosed |
| EP-0239194-A2 | Methods for preparing hydroxy compounds and intermediates | SYMBICOM AB (SE) | 1987-09-30 | — | — | EP | disclosed |