Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.40 |
| ▸ | CDC25B | P30305 | 6/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1961043 | 1.00 | GJB2 (0.45) | GJB2SSTR5SLC6A2SSTR1SSTR2 | |
| SCHEMBL8429515 | 0.90 | TACR1 (0.50) | GJB2SSTR5SLC6A2SSTR1SSTR2 | |
| SCHEMBL1780242 | 0.90 | GJB2 (0.52) | GJB2SSTR5SSTR1SSTR2SSTR4 | |
| SCHEMBL8655411 | 0.85 | GJB2 (0.52) | GJB2SSTR5SSTR1SSTR2SSTR4 | |
| SCHEMBL8653090 | 0.85 | GJB2 (0.52) | GJB2SSTR5SSTR1SSTR2SSTR4 | |
| SCHEMBL2450076 | 0.85 | TACR1 (0.45) | GJB2SLC6A2SSTR4TACR1LGALS8 | |
| SCHEMBL10524769 | 0.84 | PTPN1 (0.43) | GJB2SSTR5SLC6A2SSTR1SSTR2 | |
| SCHEMBL3151671 | 0.83 | SSTR5 (0.57) | GJB2SSTR5SLC6A2SSTR1SSTR2 | |
| SCHEMBL6382242 | 0.83 | SSTR5 (0.49) | GJB2SSTR5SLC6A2SSTR1SSTR2 | |
| SCHEMBL10524731 | 0.81 | SSTR1 (0.57) | SSTR5SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943595-B2 | Polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative | SANOFI-AVENTIS (FR) | 2011-05-17 | — | — | US | disclosed |
| EP-1322673-B1 | POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY COMPRISING AT LEAST A COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE | SANOFI AVENTIS (FR) | 2007-09-26 | — | — | EP | disclosed |
| US-20060160768-A1 | Novel polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative | SANOFI (FR) | 2006-07-20 | — | — | US | disclosed |
| US-6844329-B2 | Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative | SANOFI-SYNTHELABO (FR) | 2005-01-18 | — | — | US | disclosed |
| US-20040024197-A1 | Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative | SANOFI (FR) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160768-A1 | Novel polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative | SERPINC1, SELP, FGB | GJB2 3547/4885SSTR5 1859/4885SLC6A2 4762/4885 |
| US-20040024197-A1 | Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative | SERPINC1, SELP, FGB | GJB2 3514/4885SSTR5 1672/4885SLC6A2 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.