Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10527578 | 0.99 | EPHX2 (0.56) | EPHX2NPC1RAB9APOLBMEN1 | |
| SCHEMBL10527410 | 0.82 | EPHX2 (0.55) | EPHX2NPC1RAB9APOLBMEN1 | |
| SCHEMBL10528129 | 0.81 | EPHX2 (0.58) | EPHX2NPC1RAB9APOLBMEN1 | |
| SCHEMBL10529836 | 0.79 | EPHX2 (0.68) | EPHX2NPC1RAB9APOLBMEN1 | |
| SCHEMBL8566672 | 0.79 | PSEN1 (0.48) | — | |
| SCHEMBL10528462 | 0.77 | EPHX2 (0.71) | EPHX2NPC1RAB9APOLBMEN1 | |
| SCHEMBL2827115 | 0.77 | CYP1A2 (0.49) | — | |
| SCHEMBL5051860 | 0.77 | EPHX2 (0.68) | EPHX2NPC1RAB9APOLBMEN1 | |
| SCHEMBL10527430 | 0.76 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5053663 | 0.75 | RAB9A (0.71) | EPHX2NPC1RAB9APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797411-A | ANTITUMOR AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1989-01-10 | — | — | US | disclosed |
| EP-0253681-A2 | Cycloalkyl-substituted 4-pyridyl derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-01-20 | — | — | EP | disclosed |