Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.76 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | SHBG | P04278 | 3/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.46 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624269 | 1.00 | NR3C1 (0.76) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL12704141 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL722748 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL1274268 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL23974955 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL23974907 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL1275108 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL9070362 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL18351260 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL9223381 | 0.91 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334875-A1 | STEROIDAL 17$g(a)-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| WO-1988003534-A1 | STEROIDAL 17alpha-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1988-05-19 | — | — | WO | disclosed |