Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.57 |
| ▸ | SHBG | P04278 | 3/20 | 0.57 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.56 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23974907 | 1.00 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL1274268 | 1.00 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL722748 | 1.00 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL23974955 | 1.00 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL1275108 | 1.00 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| Anecortave Acetate SCHEMBL8472390 | 0.92 | NR3C1 (0.93) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL9070362 | 0.92 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL18351260 | 0.92 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL9223381 | 0.92 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A | |
| SCHEMBL9223554 | 0.92 | NR3C1 (0.78) | NR3C1CYP19A1HSD17B10CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326210-A1 | Enzymatic Process for Obtaining 17 Alpha-Monoesters of Cortexolone and/or its 9,11-Dehydroderivatives | CASSIOPEA S.P.A. (IT) | 2016-11-10 | — | — | US | disclosed |
| US-20160326210-A1 | Enzymatic Process for Obtaining 17 Alpha-Monoesters of Cortexolone and/or its 9,11-Dehydroderivatives | CASSIOPEA S.P.A. (IT) | 2016-11-10 | — | — | US | disclosed |
| US-20160324873-A1 | Enzymatic Process for Obtaining 17 Alpha-Monoesters of Cortexolone and/or its 9,11-Dehydroderivatives | CASSIOPEA S.P.A. (IT) | 2016-11-10 | — | — | US | disclosed |
| US-20160324873-A1 | Enzymatic Process for Obtaining 17 Alpha-Monoesters of Cortexolone and/or its 9,11-Dehydroderivatives | CASSIOPEA S.P.A. (IT) | 2016-11-10 | — | — | US | disclosed |
| US-9486458-B2 | Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives | CASSIOPEA SPA (IT) | 2016-11-08 | — | — | US | disclosed |
| US-9486458-B2 | Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives | CASSIOPEA SPA (IT) | 2016-11-08 | — | — | US | disclosed |
| US-9433628-B2 | Enzymatic process for obtaining 17α-monoesters of cortexolone and/or its 9,11-dehydroderivatives | CASSIOPEA SPA (IT) | 2016-09-06 | — | — | US | disclosed |
| US-9433628-B2 | Enzymatic process for obtaining 17α-monoesters of cortexolone and/or its 9,11-dehydroderivatives | CASSIOPEA SPA (IT) | 2016-09-06 | — | — | US | disclosed |
| EP-2503005-B1 | Cortexolone-17alpha-propionate in hydrate crystalline form IV | CASSIOPEA S P A (IT) | 2015-09-02 | — | — | EP | disclosed |
| US-8785427-B2 | Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives | COSMO DERMATOS SRL (IT) | 2014-07-22 | — | — | US | disclosed |
| US-8785427-B2 | Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives | COSMO DERMATOS SRL (IT) | 2014-07-22 | — | — | US | disclosed |
| US-20140179654-A1 | ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA- MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11- DEHYDRODERIVATIVES | COSMO SPA (IT) | 2014-06-26 | — | — | US | disclosed |
| US-20140179654-A1 | ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA- MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11- DEHYDRODERIVATIVES | COSMO SPA (IT) | 2014-06-26 | — | — | US | disclosed |
| US-20110092472-A1 | ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA- MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11- DEHYDRODERIVATIVES | COSMO SPA (IT) | 2011-04-21 | — | — | US | disclosed |
| US-20110092472-A1 | ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA- MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11- DEHYDRODERIVATIVES | COSMO SPA (IT) | 2011-04-21 | — | — | US | disclosed |
| WO-2009019138-A2 | ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA-MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11-DEHYDRODERIVATIVES | COSMO SPA (IT) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092472-A1 | ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA- MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11- DEHYDRODERIVATIVES | CYP17A1, HSD17B1, HSD11B1 | NR3C1 264/4885CYP19A1 26/4885HSD17B10 22/4885 |
| US-20160324873-A1 | Enzymatic Process for Obtaining 17 Alpha-Monoesters of Cortexolone and/or its 9,11-Dehydroderivatives | CYP17A1, HSD17B1, HSD11B1 | NR3C1 272/4885CYP19A1 25/4885HSD17B10 21/4885 |
| US-20140179654-A1 | ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA- MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11- DEHYDRODERIVATIVES | CYP17A1, HSD17B1, HSD11B1 | NR3C1 264/4885CYP19A1 26/4885HSD17B10 22/4885 |
| US-20160326210-A1 | Enzymatic Process for Obtaining 17 Alpha-Monoesters of Cortexolone and/or its 9,11-Dehydroderivatives | CYP17A1, HSD17B1, HSD11B1 | NR3C1 272/4885CYP19A1 25/4885HSD17B10 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.